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Structural basis for the nuclease activity of a bacteriophage large terminase

The DNA-packaging motor in tailed bacteriophages requires nuclease activity to ensure that the genome is packaged correctly. This nuclease activity is tightly regulated as the enzyme is inactive for the duration of DNA translocation. Here, we report the X-ray structure of the large terminase nucleas...

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Detalles Bibliográficos
Autores principales:	Smits, Callum, Chechik, Maria, Kovalevskiy, Oleg V, Shevtsov, Mikhail B, Foster, Andrew W, Alonso, Juan C, Antson, Alfred A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Scientific Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685612/ https://www.ncbi.nlm.nih.gov/pubmed/19444313 http://dx.doi.org/10.1038/embor.2009.53

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