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Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis

Archaeal RadAs are close homologues of eukaryal Rad51s (∼40% sequence identity). These recombinases promote ATP hydrolysis and a hallmark strand-exchange reaction between homologous single-stranded and double-stranded DNA sub­strates. Pairing of the 3′-overhangs located at the damaged DNA with a hom...

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Detalles Bibliográficos
Autores principales: Li, Yang, He, Yujiong, Luo, Yu
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685736/
https://www.ncbi.nlm.nih.gov/pubmed/19465774
http://dx.doi.org/10.1107/S0907444909011871