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Conservation of a conformational switch in RadA recombinase from Methanococcus maripaludis
Archaeal RadAs are close homologues of eukaryal Rad51s (∼40% sequence identity). These recombinases promote ATP hydrolysis and a hallmark strand-exchange reaction between homologous single-stranded and double-stranded DNA substrates. Pairing of the 3′-overhangs located at the damaged DNA with a hom...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685736/ https://www.ncbi.nlm.nih.gov/pubmed/19465774 http://dx.doi.org/10.1107/S0907444909011871 |