Carrier Status for the Common R501X and 2282del4 Filaggrin Mutations Is Not Associated with Hearing Phenotypes in 5377 Children from the ALSPAC Cohort

BACKGROUND: Filaggrin is a major protein in the epidermis. Several mutations in the filaggrin gene (FLG) have been associated with a number of conditions. Filaggrin is expressed in the tympanic membrane and could alter its mechanical properties, but the relationship between genetic variation in FLG...

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Detalles Bibliográficos
Autores principales: Rodriguez, Santiago, Hall, Amanda J., Granell, Raquel, McLean, W. H. Irwin, Irvine, Alan D., Palmer, Colin N. A., Smith, George Davey, Henderson, John, Day, Ian N. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685991/
https://www.ncbi.nlm.nih.gov/pubmed/19492053
http://dx.doi.org/10.1371/journal.pone.0005784

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