Cargando…
The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis
Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in pathologic conditions resulting from blocked blood vessels, including myocardial infarction and ischemic stroke. Platelet adhesion, activation, and aggregation at sites of vascular injury are regulated by a div...
Autores principales: | Senis, Yotis A., Tomlinson, Michael G., Ellison, Stuart, Mazharian, Alexandra, Lim, Jenson, Zhao, Yan, Kornerup, Kristin N., Auger, Jocelyn M., Thomas, Steve G., Dhanjal, Tarvinder, Kalia, Neena, Zhu, Jing W., Weiss, Arthur, Watson, Steve P. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686144/ https://www.ncbi.nlm.nih.gov/pubmed/19246339 http://dx.doi.org/10.1182/blood-2008-08-174318 |
Ejemplares similares
-
Analysis of preplatelets and their barbell platelet derivatives by imaging flow cytometry
por: Kemble, Samuel, et al.
Publicado: (2022) -
Mitochondrial pyruvate dehydrogenase kinases contribute to platelet function and thrombosis in mice by regulating aerobic glycolysis
por: Flora, Gagan D., et al.
Publicado: (2023) -
Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP
por: Shao, Bojing, et al.
Publicado: (2022) -
Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition
por: Billiald, Philippe, et al.
Publicado: (2022) -
Bone marrow remodeling supports hematopoiesis in response to immune thrombocytopenia progression in mice
por: Herd, Oliver J., et al.
Publicado: (2021)