Conserved Threonine Residues within the A-Loop of the Receptor NIK Differentially Regulate the Kinase Function Required for Antiviral Signaling

NSP-interacting kinase (NIK1) is a receptor-like kinase identified as a virulence target of the begomovirus nuclear shuttle protein (NSP). We found that NIK1 undergoes a stepwise pattern of phosphorylation within its activation-loop domain (A-loop) with distinct roles for different threonine residue...

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Detalles Bibliográficos
Autores principales: Santos, Anésia A., Carvalho, Claudine M., Florentino, Lilian H., Ramos, Humberto J. O., Fontes, Elizabeth P. B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686266/
https://www.ncbi.nlm.nih.gov/pubmed/19492062
http://dx.doi.org/10.1371/journal.pone.0005781

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