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Synthesis of unsymmetrically substituted biaryls via sequential lithiation of dibromobiaryls using integrated microflow systems
A microflow system consisting of micromixers and microtube reactors provides an effective method for the introduction of two electrophiles onto dibromobiaryls. Selective monolithiation of dibromobiaryls, such as 2,2′-dibromobiphenyl, 4,4′-dibromobiphenyl, 2,7-dibromo-9,9-dioctylfluorene, 2,2′-dibrom...
Autores principales: | Nagaki, Aiichiro, Takabayashi, Naofumi, Tomida, Yutaka, Yoshida, Jun-ichi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686311/ https://www.ncbi.nlm.nih.gov/pubmed/19478968 http://dx.doi.org/10.3762/bjoc.5.16 |
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