A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis

A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira’s asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction.

Detalles Bibliográficos
Autores principales: Radha Krishna, Palakodety, Lopinti, Krishnarao, Reddy, K L N
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2009
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686312/
https://www.ncbi.nlm.nih.gov/pubmed/19478909
http://dx.doi.org/10.3762/bjoc.5.14
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author Radha Krishna, Palakodety
Lopinti, Krishnarao
Reddy, K L N
author_facet Radha Krishna, Palakodety
Lopinti, Krishnarao
Reddy, K L N
author_sort Radha Krishna, Palakodety
collection PubMed
description A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira’s asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction.
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spelling pubmed-26863122009-05-28 A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis Radha Krishna, Palakodety Lopinti, Krishnarao Reddy, K L N Beilstein J Org Chem Full Research Paper A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira’s asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction. Beilstein-Institut 2009-04-24 /pmc/articles/PMC2686312/ /pubmed/19478909 http://dx.doi.org/10.3762/bjoc.5.14 Text en Copyright © 2009, Radha Krishna et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Radha Krishna, Palakodety
Lopinti, Krishnarao
Reddy, K L N
A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_full A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_fullStr A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_full_unstemmed A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_short A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis
title_sort short stereoselective synthesis of (+)-(6r,2′s)-cryptocaryalactone via ring-closing metathesis
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686312/
https://www.ncbi.nlm.nih.gov/pubmed/19478909
http://dx.doi.org/10.3762/bjoc.5.14
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