FlyBase: enhancing Drosophila Gene Ontology annotations

FlyBase (http://flybase.org) is a database of Drosophila genetic and genomic information. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. This arti...

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Detalles Bibliográficos
Autores principales: Tweedie, Susan, Ashburner, Michael, Falls, Kathleen, Leyland, Paul, McQuilton, Peter, Marygold, Steven, Millburn, Gillian, Osumi-Sutherland, David, Schroeder, Andrew, Seal, Ruth, Zhang, Haiyan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686450/
https://www.ncbi.nlm.nih.gov/pubmed/18948289
http://dx.doi.org/10.1093/nar/gkn788
Descripción
Sumario:FlyBase (http://flybase.org) is a database of Drosophila genetic and genomic information. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. This article describes recent changes to the FlyBase GO annotation strategy that are improving the quality of the GO annotation data. Many of these changes stem from our participation in the GO Reference Genome Annotation Project—a multi-database collaboration producing comprehensive GO annotation sets for 12 diverse species.

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