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Prediction of HLA-DQ8 β cell peptidome using a computational program and its relationship to autoreactive T cells

The goal was to identify HLA-DQ8-bound β cell epitopes important in the T cell response in autoimmune diabetes. We first identified HLA-DQ8 (DQA1*0301/DQB1*0302) β cell epitopes using a computational approach and then related their identification to CD4 T cell responses. The computational program (T...

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Detalles Bibliográficos
Autores principales:	Chang, Kuan Y., Unanue, Emil R.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Featured Article of the Month
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686615/ https://www.ncbi.nlm.nih.gov/pubmed/19461125 http://dx.doi.org/10.1093/intimm/dxp039

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