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Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells

In the present study, we explore the role of apoptosis signal-regulating kinase 1 (ASK1) in denbinobin-induced apoptosis in human lung adenocarcinoma (A549) cells. Denbinobin-induced cell apoptosis was attenuated by an ASK1 dominant-negative mutant (ASK1DN), two antioxidants (N-acetyl-L-cysteine (NA...

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Detalles Bibliográficos
Autores principales:	Kuo, Chen-Tzu, Chen, Bing-Chang, Yu, Chung-Chi, Weng, Chih-Ming, Hsu, Ming-Jen, Chen, Chien-Chih, Chen, Mei-Chieh, Teng, Che-Ming, Pan, Shiow-Lin, Bien, Mauo-Ying, Shih, Chung-Hung, Lin, Chien-Huang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686692/ https://www.ncbi.nlm.nih.gov/pubmed/19405983 http://dx.doi.org/10.1186/1423-0127-16-43

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