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A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages
BACKGROUND: Macrophages and dendritic cells (DCs) play key roles in host defense against HSV-1 infection. Although macrophages and DCs can be infected by herpes simplex virus type 1 (HSV-1), both cell types are resistant to HSV-1 replication. The aim of our study was to determine factor (s) that are...
Autores principales: | Mott, Kevin R, UnderHill, David, Wechsler, Steven L, Town, Terrence, Ghiasi, Homayon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686698/ https://www.ncbi.nlm.nih.gov/pubmed/19439086 http://dx.doi.org/10.1186/1743-422X-6-56 |
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