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Origin and evolution of the RIG-I like RNA helicase gene family

BACKGROUND: The DExD/H domain containing RNA helicases such as retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) are key cytosolic pattern recognition receptors (PRRs) for detecting nucleotide pathogen associated molecular patterns (PAMPs) of invading virus...

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Detalles Bibliográficos
Autores principales:	Zou, Jun, Chang, Mingxian, Nie, Pin, Secombes, Chris J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686710/ https://www.ncbi.nlm.nih.gov/pubmed/19400936 http://dx.doi.org/10.1186/1471-2148-9-85

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