Tumor-directed gene therapy in mice using a composite nonviral gene delivery system consisting of the piggyBac transposon and polyethylenimine

BACKGROUND: Compared with viral vectors, nonviral vectors are less immunogenic, more stable, safer and easier to replication for application in cancer gene therapy. However, nonviral gene delivery system has not been extensively used because of the low transfection efficiency and the short transgene...

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Detalles Bibliográficos
Autores principales: Kang, Yu, Zhang, Xiaoyan, Jiang, Wei, Wu, Chaoqun, Chen, Chunmei, Zheng, Yufang, Gu, Jianren, Xu, Congjian
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686723/
https://www.ncbi.nlm.nih.gov/pubmed/19397814
http://dx.doi.org/10.1186/1471-2407-9-126

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