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Effects of the PPAR-β agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination
BACKGROUND: Brain inflammation plays a central role in numerous brain pathologies, including multiple sclerosis (MS). Microglial cells and astrocytes are the effector cells of neuroinflammation. They can be activated also by agents such as interferon-γ (IFN-γ) and lipopolysaccharide (LPS). Peroxisom...
Autores principales: | Defaux, Antoinette, Zurich, Marie-Gabrielle, Braissant, Olivier, Honegger, Paul, Monnet-Tschudi, Florianne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687435/ https://www.ncbi.nlm.nih.gov/pubmed/19422681 http://dx.doi.org/10.1186/1742-2094-6-15 |
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