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Effects of the PPAR-β agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination

BACKGROUND: Brain inflammation plays a central role in numerous brain pathologies, including multiple sclerosis (MS). Microglial cells and astrocytes are the effector cells of neuroinflammation. They can be activated also by agents such as interferon-γ (IFN-γ) and lipopolysaccharide (LPS). Peroxisom...

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Detalles Bibliográficos
Autores principales:	Defaux, Antoinette, Zurich, Marie-Gabrielle, Braissant, Olivier, Honegger, Paul, Monnet-Tschudi, Florianne
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687435/ https://www.ncbi.nlm.nih.gov/pubmed/19422681 http://dx.doi.org/10.1186/1742-2094-6-15

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