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A Case of Acute Ventricular Capture Threshold Rise Associated with Flecainide Acetate

Antiarrhythmic agents may increase capture threshold, but this is rarely of clinical significance. Flecainide acetate, a class IC agent, is reported to have a significant effect on the myocardial capture threshold. In this presentation, we report the case of a 72-year-old male, with a previously imp...

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Detalles Bibliográficos
Autores principales: Kang, Tae Soo, Yoon, Young Won, Park, Sungha, Hong, Bum-Kee, Kim, Dongsoo, Kwon, Hyuck Moon, Kim, Hyun-Seung
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687576/
https://www.ncbi.nlm.nih.gov/pubmed/16502500
http://dx.doi.org/10.3349/ymj.2006.47.1.152
Descripción
Sumario:Antiarrhythmic agents may increase capture threshold, but this is rarely of clinical significance. Flecainide acetate, a class IC agent, is reported to have a significant effect on the myocardial capture threshold. In this presentation, we report the case of a 72-year-old male, with a previously implanted VVI pacemaker due to sick sinus syndrome, who was treated with flecainide acetate for paroxysmal atrial arrhythmia control. During the fifteenth day of treatment, an abrupt rise in the ventricular capture threshold with ventricular pacing failure was noted. The capture threshold decreased two days after discontinuation of flecainide acetate.