Phosphoinositide 3-kinase targeting by the β galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death

INTRODUCTION: Phosphoinositide 3-kinase (PI3K)-activated signalling has a critical role in the evolution of aggressive tumourigenesis and is therefore a prime target for anticancer therapy. Previously we have shown that the β galactoside binding protein (βGBP) cytokine, an antiproliferative molecule...

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Detalles Bibliográficos
Autores principales: Wells, Valerie, Mallucci, Livio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687705/
https://www.ncbi.nlm.nih.gov/pubmed/19133120
http://dx.doi.org/10.1186/bcr2217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687705/
https://www.ncbi.nlm.nih.gov/pubmed/19133120
http://dx.doi.org/10.1186/bcr2217

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