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Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors

INTRODUCTION: High expression of total HER2 protein confers poor prognosis for breast cancer patients. HER2 is a member of the HER family consisting of four receptors, HER1 to HER4. HER receptor activity is regulated by a variety of mechanisms, and phosphorylation of the C-terminal part of the HER r...

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Detalles Bibliográficos
Autores principales:	Frogne, Thomas, Laenkholm, Anne-Vibeke, Lyng, Maria B, Henriksen, Katrine Lütken, Lykkesfeldt, Anne E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687716/ https://www.ncbi.nlm.nih.gov/pubmed/19239686 http://dx.doi.org/10.1186/bcr2230

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