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Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer
INTRODUCTION: Aberrant methylation of CpG islands is a hallmark of cancer and occurs at an early stage in breast tumorigenesis. However, its impact on tumor development is not fully determined, and its potential as a diagnostic biomarker remains to be validated. Methylation profiling of invasive bre...
Autores principales: | Tommasi, Stella, Karm, Deborah L, Wu, Xiwei, Yen, Yun, Pfeifer, Gerd P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687719/ https://www.ncbi.nlm.nih.gov/pubmed/19250546 http://dx.doi.org/10.1186/bcr2233 |
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