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Identifying protein-coding genes in genomic sequences

The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference...

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Detalles Bibliográficos
Autores principales: Harrow, Jennifer, Nagy, Alinda, Reymond, Alexandre, Alioto, Tyler, Patthy, Laszlo, Antonarakis, Stylianos E, Guigó, Roderic
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687780/
https://www.ncbi.nlm.nih.gov/pubmed/19226436
http://dx.doi.org/10.1186/gb-2009-10-1-201
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author Harrow, Jennifer
Nagy, Alinda
Reymond, Alexandre
Alioto, Tyler
Patthy, Laszlo
Antonarakis, Stylianos E
Guigó, Roderic
author_facet Harrow, Jennifer
Nagy, Alinda
Reymond, Alexandre
Alioto, Tyler
Patthy, Laszlo
Antonarakis, Stylianos E
Guigó, Roderic
author_sort Harrow, Jennifer
collection PubMed
description The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference protein-coding gene sets.
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spelling pubmed-26877802010-01-30 Identifying protein-coding genes in genomic sequences Harrow, Jennifer Nagy, Alinda Reymond, Alexandre Alioto, Tyler Patthy, Laszlo Antonarakis, Stylianos E Guigó, Roderic Genome Biol Review The vast majority of the biology of a newly sequenced genome is inferred from the set of encoded proteins. Predicting this set is therefore invariably the first step after the completion of the genome DNA sequence. Here we review the main computational pipelines used to generate the human reference protein-coding gene sets. BioMed Central 2009 2009-01-30 /pmc/articles/PMC2687780/ /pubmed/19226436 http://dx.doi.org/10.1186/gb-2009-10-1-201 Text en Copyright © 2009 BioMed Central Ltd
spellingShingle Review
Harrow, Jennifer
Nagy, Alinda
Reymond, Alexandre
Alioto, Tyler
Patthy, Laszlo
Antonarakis, Stylianos E
Guigó, Roderic
Identifying protein-coding genes in genomic sequences
title Identifying protein-coding genes in genomic sequences
title_full Identifying protein-coding genes in genomic sequences
title_fullStr Identifying protein-coding genes in genomic sequences
title_full_unstemmed Identifying protein-coding genes in genomic sequences
title_short Identifying protein-coding genes in genomic sequences
title_sort identifying protein-coding genes in genomic sequences
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687780/
https://www.ncbi.nlm.nih.gov/pubmed/19226436
http://dx.doi.org/10.1186/gb-2009-10-1-201
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