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Predicting and understanding the stability of G-quadruplexes

Motivation: G-quadruplexes are stable four-stranded guanine-rich structures that can form in DNA and RNA. They are an important component of human telomeres and play a role in the regulation of transcription and translation. The biological significance of a G-quadruplex is crucially linked with its...

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Detalles Bibliográficos
Autores principales: Stegle, Oliver, Payet, Linda, Mergny, Jean-Louis, MacKay, David J. C., Leon, Julian Huppert
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687964/
https://www.ncbi.nlm.nih.gov/pubmed/19478012
http://dx.doi.org/10.1093/bioinformatics/btp210