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Modeling interactions between adjacent nucleosomes improves genome-wide predictions of nucleosome occupancy

Motivation: Understanding the mechanisms that govern nucleosome positioning over genomes in vivo is essential for unraveling the role of chromatin organization in transcriptional regulation. Until now, models for predicting genome-wide nucleosome occupancy have assumed that the DNA associations of n...

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Detalles Bibliográficos
Autores principales: Lubliner, Shai, Segal, Eran
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687970/
https://www.ncbi.nlm.nih.gov/pubmed/19478009
http://dx.doi.org/10.1093/bioinformatics/btp216