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Viruses selectively mutate their CD8+ T-cell epitopes—a large-scale immunomic analysis

Motivation: Viruses employ various means to evade immune detection. One common evasion strategy is the removal of CD8+cytotoxic T-lymphocyte epitopes. We here use a combination of multiple bioinformatic tools and large amount of genomic data to compute the epitope repertoire presented by over 1300 v...

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Detalles Bibliográficos
Autores principales: Vider-Shalit, Tal, Sarid, Ronit, Maman, Kobi, Tsaban, Lea, Levi, Ran, Louzoun, Yoram
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687975/
https://www.ncbi.nlm.nih.gov/pubmed/19478014
http://dx.doi.org/10.1093/bioinformatics/btp221