STAT1 Pathway Mediates Amplification of Metastatic Potential and Resistance to Therapy

BACKGROUND: Traditionally IFN/STAT1 signaling is connected with an anti-viral response and pro-apoptotic tumor-suppressor functions. Emerging functions of a constitutively activated IFN/STAT1 pathway suggest an association with an aggressive tumor phenotype. We hypothesized that tumor clones that co...

Descripción completa

Detalles Bibliográficos
Autores principales: Khodarev, Nikolai N., Roach, Paul, Pitroda, Sean P., Golden, Daniel W., Bhayani, Mihir, Shao, Michael Y., Darga, Thomas E., Beveridge, Mara G., Sood, Ravi F., Sutton, Harold G., Beckett, Michael A., Mauceri, Helena J., Posner, Mitchell C., Weichselbaum, Ralph R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688034/
https://www.ncbi.nlm.nih.gov/pubmed/19503789
http://dx.doi.org/10.1371/journal.pone.0005821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688034/
https://www.ncbi.nlm.nih.gov/pubmed/19503789
http://dx.doi.org/10.1371/journal.pone.0005821

Ejemplares similares