Lipid Rafts and Clathrin Cooperate in the Internalization of PrP(C) in Epithelial FRT Cells

BACKGROUND: The cellular prion protein (PrP(C)) plays a key role in the pathogenesis of Transmissible Spongiform Encephalopathies in which the protein undergoes post-translational conversion to the infectious form (PrP(Sc)). Although endocytosis appears to be required for this conversion, the mechan...

Descripción completa

Detalles Bibliográficos
Autores principales: Sarnataro, Daniela, Caputo, Anna, Casanova, Philippe, Puri, Claudia, Paladino, Simona, Tivodar, Simona S., Campana, Vincenza, Tacchetti, Carlo, Zurzolo, Chiara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688078/
https://www.ncbi.nlm.nih.gov/pubmed/19503793
http://dx.doi.org/10.1371/journal.pone.0005829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688078/
https://www.ncbi.nlm.nih.gov/pubmed/19503793
http://dx.doi.org/10.1371/journal.pone.0005829

Ejemplares similares