Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis

INTRODUCTION: Septic encephalopathy secondary to a breakdown of the blood-brain barrier (BBB) is a known complication of sepsis. However, its pathophysiology remains unclear. The present study investigated the effect of complement C5a blockade in preventing BBB damage and pituitary dysfunction durin...

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Detalles Bibliográficos
Autores principales: Flierl, Michael A, Stahel, Philip F, Rittirsch, Daniel, Huber-Lang, Markus, Niederbichler, Andreas D, Hoesel, L Marco, Touban, Basel M, Morgan, Steven J, Smith, Wade R, Ward, Peter A, Ipaktchi, Kyros
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688129/
https://www.ncbi.nlm.nih.gov/pubmed/19196477
http://dx.doi.org/10.1186/cc7710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688129/
https://www.ncbi.nlm.nih.gov/pubmed/19196477
http://dx.doi.org/10.1186/cc7710

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