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The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus

The increased burden of cardiovascular disease in patients with rheumatoid arthritis and systemic lupus erythematosus has recently become the focus of intense investigation. Proatherogenic risk factors and dysregulated inflammation are the main culprits, leading to enhanced atherosclerosis in subgro...

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Detalles Bibliográficos
Autores principales: Full, Louise E, Ruisanchez, Cristina, Monaco, Claudia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688172/
https://www.ncbi.nlm.nih.gov/pubmed/19435478
http://dx.doi.org/10.1186/ar2631
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author Full, Louise E
Ruisanchez, Cristina
Monaco, Claudia
author_facet Full, Louise E
Ruisanchez, Cristina
Monaco, Claudia
author_sort Full, Louise E
collection PubMed
description The increased burden of cardiovascular disease in patients with rheumatoid arthritis and systemic lupus erythematosus has recently become the focus of intense investigation. Proatherogenic risk factors and dysregulated inflammation are the main culprits, leading to enhanced atherosclerosis in subgroups of patients with inflammatory diseases. Common molecular pathways shared by atherosclerosis and inflammatory disease may be involved. In this review we map the key determinants of the increased incidence of cardiovascular disease in patients with inflammatory diseases at each step of the atherogenesis.
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spelling pubmed-26881722009-10-03 The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus Full, Louise E Ruisanchez, Cristina Monaco, Claudia Arthritis Res Ther Review The increased burden of cardiovascular disease in patients with rheumatoid arthritis and systemic lupus erythematosus has recently become the focus of intense investigation. Proatherogenic risk factors and dysregulated inflammation are the main culprits, leading to enhanced atherosclerosis in subgroups of patients with inflammatory diseases. Common molecular pathways shared by atherosclerosis and inflammatory disease may be involved. In this review we map the key determinants of the increased incidence of cardiovascular disease in patients with inflammatory diseases at each step of the atherogenesis. BioMed Central 2009 2009-04-03 /pmc/articles/PMC2688172/ /pubmed/19435478 http://dx.doi.org/10.1186/ar2631 Text en Copyright © 2009 BioMed Central Ltd
spellingShingle Review
Full, Louise E
Ruisanchez, Cristina
Monaco, Claudia
The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
title The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
title_full The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
title_fullStr The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
title_full_unstemmed The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
title_short The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
title_sort inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688172/
https://www.ncbi.nlm.nih.gov/pubmed/19435478
http://dx.doi.org/10.1186/ar2631
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