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The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus
The increased burden of cardiovascular disease in patients with rheumatoid arthritis and systemic lupus erythematosus has recently become the focus of intense investigation. Proatherogenic risk factors and dysregulated inflammation are the main culprits, leading to enhanced atherosclerosis in subgro...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688172/ https://www.ncbi.nlm.nih.gov/pubmed/19435478 http://dx.doi.org/10.1186/ar2631 |
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author | Full, Louise E Ruisanchez, Cristina Monaco, Claudia |
author_facet | Full, Louise E Ruisanchez, Cristina Monaco, Claudia |
author_sort | Full, Louise E |
collection | PubMed |
description | The increased burden of cardiovascular disease in patients with rheumatoid arthritis and systemic lupus erythematosus has recently become the focus of intense investigation. Proatherogenic risk factors and dysregulated inflammation are the main culprits, leading to enhanced atherosclerosis in subgroups of patients with inflammatory diseases. Common molecular pathways shared by atherosclerosis and inflammatory disease may be involved. In this review we map the key determinants of the increased incidence of cardiovascular disease in patients with inflammatory diseases at each step of the atherogenesis. |
format | Text |
id | pubmed-2688172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26881722009-10-03 The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus Full, Louise E Ruisanchez, Cristina Monaco, Claudia Arthritis Res Ther Review The increased burden of cardiovascular disease in patients with rheumatoid arthritis and systemic lupus erythematosus has recently become the focus of intense investigation. Proatherogenic risk factors and dysregulated inflammation are the main culprits, leading to enhanced atherosclerosis in subgroups of patients with inflammatory diseases. Common molecular pathways shared by atherosclerosis and inflammatory disease may be involved. In this review we map the key determinants of the increased incidence of cardiovascular disease in patients with inflammatory diseases at each step of the atherogenesis. BioMed Central 2009 2009-04-03 /pmc/articles/PMC2688172/ /pubmed/19435478 http://dx.doi.org/10.1186/ar2631 Text en Copyright © 2009 BioMed Central Ltd |
spellingShingle | Review Full, Louise E Ruisanchez, Cristina Monaco, Claudia The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus |
title | The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus |
title_full | The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus |
title_fullStr | The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus |
title_full_unstemmed | The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus |
title_short | The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus |
title_sort | inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688172/ https://www.ncbi.nlm.nih.gov/pubmed/19435478 http://dx.doi.org/10.1186/ar2631 |
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