Do synovial biopsies help to support evidence for involvement of innate immunity in the immunopathology of Behçet's disease?

Behçet's disease is a complex vasculitis of unknown etiology. Abundant neutrophils suggest the involvement of innate immunity. Cytokines are skewed to the T-helper-1 pattern. Few sterile organs are easily accessible for analysis in Behçet's disease. Cañete and coworkers identify inflamed j...

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Detalles Bibliográficos
Autores principales: van Laar, Jan AM, Kappen, Jasper H, van Daele, Paul LA, van Hagen, P Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688194/
https://www.ncbi.nlm.nih.gov/pubmed/19439057
http://dx.doi.org/10.1186/ar2657
Descripción
Sumario:Behçet's disease is a complex vasculitis of unknown etiology. Abundant neutrophils suggest the involvement of innate immunity. Cytokines are skewed to the T-helper-1 pattern. Few sterile organs are easily accessible for analysis in Behçet's disease. Cañete and coworkers identify inflamed joints as a feasible model and suggest the involvement of innate immunity in Behçet's disease.

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