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Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc

INTRODUCTION: Asporin, also known as periodontal ligament-associated protein 1 (PLAP1), is a member of the family of small leucine-rich proteoglycan (SLRP) family. It is present within the cartilage extracellular matrix (ECM), and is reported to have a genetic association with osteoarthritis. Its D1...

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Detalles Bibliográficos
Autores principales: Gruber, Helen E, Ingram, Jane A, Hoelscher, Gretchen L, Zinchenko, Natalia, Hanley, Edward N, Sun, Yubo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688197/
https://www.ncbi.nlm.nih.gov/pubmed/19327154
http://dx.doi.org/10.1186/ar2660