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Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent
INTRODUCTION: The rheumatoid arthritis (RA) synovium is characterised by the presence of an aggressive population of activated synovial fibroblasts (RASFs) that are prominently involved in the destruction of articular cartilage and bone. Accumulating evidence suggests that RASFs are relatively resis...
Autores principales: | Pundt, Noreen, Peters, Marvin A, Wunrau, Christina, Strietholt, Simon, Fehrmann, Carsten, Neugebauer, Katja, Seyfert, Christine, van Valen, Frans, Pap, Thomas, Meinecke, Ingmar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688248/ https://www.ncbi.nlm.nih.gov/pubmed/19196465 http://dx.doi.org/10.1186/ar2607 |
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