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Susceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent

INTRODUCTION: The rheumatoid arthritis (RA) synovium is characterised by the presence of an aggressive population of activated synovial fibroblasts (RASFs) that are prominently involved in the destruction of articular cartilage and bone. Accumulating evidence suggests that RASFs are relatively resis...

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Detalles Bibliográficos
Autores principales: Pundt, Noreen, Peters, Marvin A, Wunrau, Christina, Strietholt, Simon, Fehrmann, Carsten, Neugebauer, Katja, Seyfert, Christine, van Valen, Frans, Pap, Thomas, Meinecke, Ingmar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688248/
https://www.ncbi.nlm.nih.gov/pubmed/19196465
http://dx.doi.org/10.1186/ar2607

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