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Protein function annotation by homology-based inference

With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein fu...

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Detalles Bibliográficos
Autores principales: Loewenstein, Yaniv, Raimondo, Domenico, Redfern, Oliver C, Watson, James, Frishman, Dmitrij, Linial, Michal, Orengo, Christine, Thornton, Janet, Tramontano, Anna
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688287/
https://www.ncbi.nlm.nih.gov/pubmed/19226439
http://dx.doi.org/10.1186/gb-2009-10-2-207
Descripción
Sumario:With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein function based on protein sequence and structure.