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Topoisomerase I and IIα protein expression in primary colorectal cancer and recurrences following 5-fluorouracil-based adjuvant chemotherapy

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PURPOSE: Human DNA topoisomerases I and II (topo-I and -II) are essential for vital cellular processes such as DNA replication, transcription, translation, recombination, and repair. In the present study, we correlate topo-I and -II expression and outcome after chemotherapy in primary and relapsed c...

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Detalles Bibliográficos
Autores principales:	Tsavaris, Nicolas, Lazaris, Andreas, Kosmas, Christos, Gouveris, Panagiotis, Kavantzas, Nikolaos, Kopterides, Petros, Papathomas, Thomas, Arapogiannis, George, Zorzos, Haralambos, Kyriakou, Vassiliki, Patsouris, Efstathios
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2008
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688619/ https://www.ncbi.nlm.nih.gov/pubmed/19083133 http://dx.doi.org/10.1007/s00280-008-0886-4

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