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Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

Intracellular malaria parasites require lipids for growth and replication. They possess a prokaryotic type II fatty acid synthesis (FAS II) pathway that localizes to the apicoplast plastid organelle and is assumed to be necessary for pathogenic blood stage replication. However, the importance of FAS...

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Detalles Bibliográficos
Autores principales: Vaughan, Ashley M, O'Neill, Matthew T, Tarun, Alice S, Camargo, Nelly, Phuong, Thuan M, Aly, Ahmed S I, Cowman, Alan F, Kappe, Stefan H I
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688669/
https://www.ncbi.nlm.nih.gov/pubmed/19068099
http://dx.doi.org/10.1111/j.1462-5822.2008.01270.x