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Thermal and chemical unfolding and refolding of a eukaryotic sodium channel

Voltage-gated sodium channels are dynamic membrane proteins essential for signaling in nervous and muscular systems. They undergo substantial conformational changes associated with the closed, open and inactivated states. However, little information is available regarding their conformational stabil...

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Detalles Bibliográficos
Autores principales: Charalambous, Kalypso, O'Reilly, A.O., Bullough, Per A., Wallace, B.A.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688679/
https://www.ncbi.nlm.nih.gov/pubmed/19232514
http://dx.doi.org/10.1016/j.bbamem.2009.02.005