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Melanopsin as a Sleep Modulator: Circadian Gating of the Direct Effects of Light on Sleep and Altered Sleep Homeostasis in Opn4(−/−) Mice
Light influences sleep and alertness either indirectly through a well-characterized circadian pathway or directly through yet poorly understood mechanisms. Melanopsin (Opn4) is a retinal photopigment crucial for conveying nonvisual light information to the brain. Through extensive characterization o...
Autores principales: | Tsai, Jessica W., Hannibal, Jens, Hagiwara, Grace, Colas, Damien, Ruppert, Elisabeth, Ruby, Norman F., Heller, H. Craig, Franken, Paul, Bourgin, Patrice |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688840/ https://www.ncbi.nlm.nih.gov/pubmed/19513122 http://dx.doi.org/10.1371/journal.pbio.1000125 |
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