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Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure
A method is proposed that finds enriched pathways relevant to a studied condition using the measured molecular data and also the structural information of the pathway viewed as a network of nodes and edges. Tests are performed using simulated data and genomic data sets and the method is compared to...
Autores principales: | Thomas, Reuben, Gohlke, Julia M, Stopper, Geffrey F, Parham, Frederick M, Portier, Christopher J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688935/ https://www.ncbi.nlm.nih.gov/pubmed/19393085 http://dx.doi.org/10.1186/gb-2009-10-4-r44 |
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