Peroxisome proliferator-activated receptor-γ protects ERBB2-positive breast cancer cells from palmitate toxicity

INTRODUCTION: Accumulation of fatty acids and neutral lipids in nonadipose tissues is cytotoxic. We recently showed that ERBB2-positive breast cancer cells produce significantly high amounts of fats, because of overexpression of the peroxisome proliferator-activated receptor (PPAR)γ-binding protein...

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Detalles Bibliográficos
Autores principales: Kourtidis, Antonis, Srinivasaiah, Rekha, Carkner, Richard D, Brosnan, M Julia, Conklin, Douglas S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688944/
https://www.ncbi.nlm.nih.gov/pubmed/19298655
http://dx.doi.org/10.1186/bcr2240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688944/
https://www.ncbi.nlm.nih.gov/pubmed/19298655
http://dx.doi.org/10.1186/bcr2240

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