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The pathway of HCV mRNA recruitment to the human ribosome
Eukaryotic protein synthesis begins with mRNA positioning in the ribosomal decoding channel in a process typically controlled by translation initiation factors. Some viruses utilize an internal ribosome entry site (IRES) in their mRNA to harness ribosomes independently of initiation factors. We show...
Autores principales: | Fraser, Christopher S., Hershey, John W. B., Doudna, Jennifer A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689074/ https://www.ncbi.nlm.nih.gov/pubmed/19287397 http://dx.doi.org/10.1038/nsmb.1572 |
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