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Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome

BACKGROUND: To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer. CASE PRESENTATION: Cycle monitoring in IVF identifie...

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Autores principales: Walsh, David J, Sills, Eric Scott, Shkrobot, Lyuda V, Gleeson, Noreen C, Sheppard, Mary N, Walsh, Anthony PH
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689217/
https://www.ncbi.nlm.nih.gov/pubmed/19442277
http://dx.doi.org/10.1186/1477-7819-7-46
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author Walsh, David J
Sills, Eric Scott
Shkrobot, Lyuda V
Gleeson, Noreen C
Sheppard, Mary N
Walsh, Anthony PH
author_facet Walsh, David J
Sills, Eric Scott
Shkrobot, Lyuda V
Gleeson, Noreen C
Sheppard, Mary N
Walsh, Anthony PH
author_sort Walsh, David J
collection PubMed
description BACKGROUND: To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer. CASE PRESENTATION: Cycle monitoring in IVF identified an abnormal ovarian lesion which was subjected to ultrasound-guided needle aspiration. Cytology suggested malignancy, and unilateral oophorectomy was performed after formal staging. After surgery, the patient underwent an anonymous donor oocyte IVF cycle which established a viable twin intrauterine pregnancy. No recurrence of cancer has been detected in the >72 month follow-up interval; mother and twin daughters continue to do well. CONCLUSION: Suspicious adnexal structures noted during controlled ovarian hyperstimulation for IVF warrant assessment, and this report confirms the role of aspiration cytology in such cases. If uterine conservation is possible, successful livebirth can be achieved from IVF if donor oocyes are utilised, as described here.
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spelling pubmed-26892172009-06-02 Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome Walsh, David J Sills, Eric Scott Shkrobot, Lyuda V Gleeson, Noreen C Sheppard, Mary N Walsh, Anthony PH World J Surg Oncol Case Report BACKGROUND: To present a diagnostic evaluation and treatment strategy for serous adenocarcinoma of the ovary discovered during an in vitro fertilisation (IVF) sequence, and report on reproductive outcome after tumour resection and embryo transfer. CASE PRESENTATION: Cycle monitoring in IVF identified an abnormal ovarian lesion which was subjected to ultrasound-guided needle aspiration. Cytology suggested malignancy, and unilateral oophorectomy was performed after formal staging. After surgery, the patient underwent an anonymous donor oocyte IVF cycle which established a viable twin intrauterine pregnancy. No recurrence of cancer has been detected in the >72 month follow-up interval; mother and twin daughters continue to do well. CONCLUSION: Suspicious adnexal structures noted during controlled ovarian hyperstimulation for IVF warrant assessment, and this report confirms the role of aspiration cytology in such cases. If uterine conservation is possible, successful livebirth can be achieved from IVF if donor oocyes are utilised, as described here. BioMed Central 2009-05-14 /pmc/articles/PMC2689217/ /pubmed/19442277 http://dx.doi.org/10.1186/1477-7819-7-46 Text en Copyright © 2009 Walsh et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Walsh, David J
Sills, Eric Scott
Shkrobot, Lyuda V
Gleeson, Noreen C
Sheppard, Mary N
Walsh, Anthony PH
Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome
title Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome
title_full Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome
title_fullStr Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome
title_full_unstemmed Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome
title_short Ovarian serous adenocarcinoma identified during IVF: diagnostic approach, surgical management, and reproductive outcome
title_sort ovarian serous adenocarcinoma identified during ivf: diagnostic approach, surgical management, and reproductive outcome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689217/
https://www.ncbi.nlm.nih.gov/pubmed/19442277
http://dx.doi.org/10.1186/1477-7819-7-46
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