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Transcriptional signatures of Itk-deficient CD3(+), CD4(+ )and CD8(+ )T-cells

BACKGROUND: The Tec-family kinase Itk plays an important role during T-cell activation and function, and controls also conventional versus innate-like T-cell development. We have characterized the transcriptome of Itk-deficient CD3(+ )T-cells, including CD4(+ )and CD8(+ )subsets, using Affymetrix mi...

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Detalles Bibliográficos
Autores principales:	Blomberg, K Emelie M, Boucheron, Nicole, Lindvall, Jessica M, Yu, Liang, Raberger, Julia, Berglöf, Anna, Ellmeier, Wilfried, Smith, CI Edvard
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689280/ https://www.ncbi.nlm.nih.gov/pubmed/19450280 http://dx.doi.org/10.1186/1471-2164-10-233

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