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Prediction of IBD based on population history for fine gene mapping

A novel multiple regression method (RM) is developed to predict identity-by-descent probabilities at a locus L (IBD(L)), among individuals without pedigree, given information on surrounding markers and population history. These IBD(L )probabilities are a function of the increase in linkage disequili...

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Detalles Bibliográficos
Autores principales: Hernández-Sánchez, Jules, Haley, Chris S, Woolliams, John A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689283/
https://www.ncbi.nlm.nih.gov/pubmed/16635447
http://dx.doi.org/10.1186/1297-9686-38-3-231