Inhaled aerosolised recombinant human activated protein C ameliorates endotoxin-induced lung injury in anaesthetised sheep

INTRODUCTION: We recently demonstrated that intravenously infused recombinant human activated protein C (APC) attenuates ovine lipopolysaccharide (LPS)-induced lung injury. In this study, our aim was to find out whether treatment with inhaled aerosolised APC (inhAPC) prevents formation of increased...

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Detalles Bibliográficos
Autores principales: Waerhaug, Kristine, Kuzkov, Vsevolod V, Kuklin, Vladimir N, Mortensen, Rica, Nordhus, Kåre C, Kirov, Mikhail Y, Bjertnaes, Lars J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689497/
https://www.ncbi.nlm.nih.gov/pubmed/19356243
http://dx.doi.org/10.1186/cc7777

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