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Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity

INTRODUCTION: Acetaminophen (APAP) toxicity is the most common cause of acute liver failure in the US and Europe. Massive hepatocyte necrosis is the predominant feature of APAP-induced acute liver injury (ALI). Liver regeneration is a vital process for survival after a toxic insult, it occurs at a r...

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Detalles Bibliográficos
Autores principales: Yang, Runkuan, Miki, Keita, He, Xin, Killeen, Meaghan E, Fink, Mitchell P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689502/
https://www.ncbi.nlm.nih.gov/pubmed/19358737
http://dx.doi.org/10.1186/cc7782

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