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Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity
INTRODUCTION: Acetaminophen (APAP) toxicity is the most common cause of acute liver failure in the US and Europe. Massive hepatocyte necrosis is the predominant feature of APAP-induced acute liver injury (ALI). Liver regeneration is a vital process for survival after a toxic insult, it occurs at a r...
Autores principales: | Yang, Runkuan, Miki, Keita, He, Xin, Killeen, Meaghan E, Fink, Mitchell P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689502/ https://www.ncbi.nlm.nih.gov/pubmed/19358737 http://dx.doi.org/10.1186/cc7782 |
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