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Numerical Analysis of Etoposide Induced DNA Breaks

BACKGROUND: Etoposide is a cancer drug that induces strand breaks in cellular DNA by inhibiting topoisomerase II (topoII) religation of cleaved DNA molecules. Although DNA cleavage by topoisomerase II always produces topoisomerase II-linked DNA double-strand breaks (DSBs), the action of etoposide al...

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Detalles Bibliográficos
Autores principales:	Muslimović, Aida, Nyström, Susanne, Gao, Yue, Hammarsten, Ola
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689654/ https://www.ncbi.nlm.nih.gov/pubmed/19516899 http://dx.doi.org/10.1371/journal.pone.0005859

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