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Polycomb Group Genes: Keeping Stem Cell Activity in Balance
Overexpression of Polycomb group genes is often associated with cancer development, whereas complete deletion results in loss of stem cell activity. New studies show that partial loss of function of Polycomb group genes enhances the activity of blood stem/progenitor cells.
Autores principales: | Sauvageau, Martin, Sauvageau, Guy |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689701/ https://www.ncbi.nlm.nih.gov/pubmed/18447587 http://dx.doi.org/10.1371/journal.pbio.0060113 |
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