Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen

Y-box protein (YB)-1 of the cold-shock protein family functions in gene transcription and RNA processing. Extracellular functions have not been reported, but the YB-1 staining pattern in inflammatory glomerular diseases, without adherence to cell boundaries, suggests an extracellular occurrence. Her...

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Detalles Bibliográficos
Autores principales: Frye, Björn C, Halfter, Sarah, Djudjaj, Sonja, Muehlenberg, Philipp, Weber, Susanne, Raffetseder, Ute, En-Nia, Abdelaziz, Knott, Hanna, Baron, Jens M, Dooley, Steven, Bernhagen, Jürgen, Mertens, Peter R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Scientific Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690452/
https://www.ncbi.nlm.nih.gov/pubmed/19483673
http://dx.doi.org/10.1038/embor.2009.81

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