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Functional recombinant MHC class II molecules and high-throughput peptide-binding assays

BACKGROUND: Molecules of the class II major histocompability complex (MHC-II) specifically bind and present exogenously derived peptide epitopes to CD4+ T helper cells. The extreme polymorphism of the MHC-II hampers the complete analysis of peptide binding. It is also a significant hurdle in the gen...

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Detalles Bibliográficos
Autores principales:	Justesen, Sune, Harndahl, Mikkel, Lamberth, Kasper, Nielsen, Lise-Lotte B, Buus, Søren
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690590/ https://www.ncbi.nlm.nih.gov/pubmed/19416502 http://dx.doi.org/10.1186/1745-7580-5-2

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