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Mutations in the paralogous human α-globin genes yielding identical hemoglobin variants

The human α-globin genes are paralogues, sharing a high degree of DNA sequence similarity and producing an identical α-globin chain. Over half of the α-globin structural variants reported to date are only characterized at the amino acid level. It is likely that a fraction of these variants, with phe...

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Detalles Bibliográficos
Autores principales:	Moradkhani, Kamran, Préhu, Claude, Old, John, Henderson, Shirley, Balamitsa, Vera, Luo, Hong-Yuan, Poon, Man-Chiu, Chui, David H. K., Wajcman, Henri, Patrinos, George P.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2008
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690850/ https://www.ncbi.nlm.nih.gov/pubmed/18923834 http://dx.doi.org/10.1007/s00277-008-0624-3

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