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Mycophenolic acid formulations in adult renal transplantation – update on efficacy and tolerability

The description more than 30 years ago of the role of de novo purine synthesis in T and B lymphocytes clonal proliferation opened the possibility for selective immunosuppression by targeting specific enzymatic pathways. Mycophenolic acid (MPA) blocks the key enzyme inosine monophosphate dehydrogenas...

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Detalles Bibliográficos
Autores principales: Golshayan, Déla, Pascual, M, Vogt, Bruno
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2690976/
https://www.ncbi.nlm.nih.gov/pubmed/19753127