Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells

BACKGROUND: Ovarian cancer is the leading cause of mortality from gynecological malignancies, often undetectable in early stages. The difficulty of detecting the disease in its early stages and the propensity of ovarian cancer cells to develop resistance to known chemotherapeutic treatments dramatic...

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Detalles Bibliográficos
Autores principales: Kumar, Sanjeev, Bryant, Christopher S, Chamala, Sreedhar, Qazi, Aamer, Seward, Shelly, Pal, Jagannath, Steffes, Christopher P, Weaver, Donald W, Morris, Robert, Malone, John M, Shammas, Masood A, Prasad, Madhu, Batchu, Ramesh B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691728/
https://www.ncbi.nlm.nih.gov/pubmed/19386116
http://dx.doi.org/10.1186/1476-4598-8-26

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