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siRNA inhibition of telomerase enhances the anti-cancer effect of doxorubicin in breast cancer cells
BACKGROUND: Doxorubicin is an effective breast cancer drug but is hampered by a severe, dose-dependent toxicity. Concomitant administration of doxorubicin and another cancer drug may be able to sensitize tumor cells to the cytotoxicity of doxorubicin and lowers the therapeutic dosage. In this study,...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691745/ https://www.ncbi.nlm.nih.gov/pubmed/19416503 http://dx.doi.org/10.1186/1471-2407-9-133 |